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Smoking e-cigarettes or “vaping” has been marketed as an alternative to traditional tobacco cigarettes to help existing smokers “kick the habit”. However, their popularity is also rising among non-smoking adolescents – from 2017–2018 e-cigarette use increased by a staggering 78% in high school students – with the primary appeal cited as being the variety of available flavors. But how safe are the ingredients in e-cigarettes? Here we highlight some of the studies exploring e-cigarette safety, published during 2019.